Article
Role of PTEN gene in progression of prostate cancer.
Urology journal - 1 Jan 2007
Pourmand Gholamreza, Ziaee Abed-Ali, Abedi Amir Reza, Mehrsai Abdolrasoul, Alavi Hossein Afshin, Ahmadi Ali, Saadati Hamid Reza
Abstract excerpt
INTRODUCTION: The aim of this study was to clarify the role of PTEN gene in progression of prostate cancer. MATERIALS AND METHODS: A total of 51 formalin-fixed paraffin-embedded specimens of prostate cancer were analyzed for PTEN mutations. Tissue microdissection and polymerase chain reaction/single-strand conformation polymorphism methods were used. Clinical and pathologic data of the patients were reviewed with...
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