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Article

Loss of Dickkopf 3 Promotes the Tumorigenesis of Basal Breast Cancer

28 Jul 2016

Abstract excerpt

Dickkopf 3 (DKK3) has been associated with tumor suppression of various tumor entities including breast cancer. However, the functional impact of DKK3 on the tumorigenesis of distinct molecular breast cancer subtypes has not been considered so far. Therefore, we initiated a study analyzing the subtype-specific DKK3 expression pattern as well as its prognostic and functional impact with respect to breast cancer...

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PMID: 27467270
DOI: 10.1371/journal.pone.0160077

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