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Article

Imputation of DNA Methylation Levels in the Brain Implicates a Risk Factor for Parkinson's Disease.

Genetics - 1 Oct 2016

Rawlik Konrad, Rowlatt Amy, Tenesa Albert

Abstract excerpt

Understanding how genetic variation affects intermediate phenotypes, like DNA methylation or gene expression, and how these in turn vary with complex human disease provides valuable insight into disease etiology. However, intermediate phenotypes are typically tissue and developmental stage specific, making relevant phenotypes difficult to assay. Assembling large case-control cohorts, necessary to achieve...

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Identifiers

PMID: 27466229
DOI: 10.1534/genetics.115.185967
PMCID: PMC5068861

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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