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Article

Biosynthetic engineering of nonribosomal peptide synthetases.

Journal of peptide science : an official publication of the European Peptide Society - 1 Sept 2016

Kries Hajo

Abstract excerpt

From the evolutionary melting pot of natural product synthetase genes, microorganisms elicit antibiotics, communication tools, and iron scavengers. Chemical biologists manipulate these genes to recreate similarly diverse and potent biological activities not on evolutionary time scales but within months. Enzyme engineering has progressed considerably in recent years and offers new screening, modelling, and design...

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Identifiers

PMID: 27465074
DOI: 10.1002/psc.2907

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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