Article
Genetic polymorphisms influence on the response to clopidogrel in peripheral artery disease patients following percutaneous transluminal angioplasty.
Pharmacogenomics - 1 Aug 2016
Díaz-Villamarín Xando, Dávila-Fajardo Cristina Lucía, Martínez-González Luis Javier, Carmona-Sáez Pedro, Sánchez-Ramos Jesús, Álvarez Cubero María Jesús, Salmerón-Febres Luis Miguel, Cabeza Barrera Jose, Fernández-Quesada Fidel
Abstract excerpt
AIM: To study the association of ABCB1 and CYP2C19 polymorphisms and the clopidogrel response in Spanish peripheral artery disease patients following percutaneous transluminal angioplasty (PTA) and to perform a meta-analysis. MATERIALS & METHODS: 72 patients were recruited and 122 patients included in the meta-analysis. We evaluated the effect of ABCB1 3435 C>T, CYP2C19*2 and CYP2C19*3 and primary end point...
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