Article
Genetic Polymorphisms and Clopidogrel Efficacy for Acute Ischemic Stroke or Transient Ischemic Attack: A Systematic Review and Meta-Analysis.
Circulation - 3 Jan 2017
Pan Yuesong, Chen Weiqi, Xu Yun, Yi Xingyang, Han Yan, Yang Qingwu, Li Xin, Huang Li'an, Johnston S Claiborne, Zhao Xingquan, Liu Liping, Zhang Qi, Wang Guangyao, Wang Yongjun, Wang Yilong
Abstract excerpt
BACKGROUND: The association of genetic polymorphisms and clopidogrel efficacy in patients with ischemic stroke or transient ischemic attack (TIA) remains controversial. We performed a systematic review and meta-analysis to assess the association between genetic polymorphisms, especially CYP2C19 genotype, and clopidogrel efficacy for ischemic stroke or TIA. METHODS: We conducted a comprehensive search of PubMed...
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