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Article

Systematic candidate gene investigations in the SPA2 locus (9q32) show an association between TNFSF8 and susceptibility to spondylarthritis.

Arthritis and rheumatism - 1 Jul 2011

Zinovieva Elena, Kadi Amir, Letourneur Franck, Cagnard Nicolas, Izac Brigitte, Vigier Agathe, Said-Nahal Roula, Elewaut Dirk, de Vlam Kurt, Pimentel-Santos Fernando, Chiocchia Gilles, Breban Maxime

Abstract excerpt

OBJECTIVE: Our group previously identified a new susceptibility region linked to spondylarthritis (SpA) on chromosome 9q31-34. Fine mapping of this SPA2 locus allowed us to refine the peak of linkage to a 1.3-Mb interval. The objective of this study was to resequence most positional candidate genes lying in that region, to identify polymorphisms, and to examine their association with SpA. METHODS: Variants...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21480186
DOI: 10.1002/art.30377

Genes

TNFSF8
AMBP
KIF12
ORM1
ORM2
TNFSF15

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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