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Article

GSTM1 and GSTP1, but not GSTT1 genetic polymorphisms are associated with chronic myeloid leukemia risk and treatment response.

Cancer epidemiology - 1 Oct 2016

Weich Natalia, Ferri Cristian, Moiraghi Beatriz, Bengió Raquel, Giere Isabel, Pavlovsky Carolina, Larripa Irene B, Fundia Ariela F

Abstract excerpt

BACKGROUND: Chronic myeloid leukemia (CML) is associated to the BCR-ABL1 oncogene and can successfully be treated with tyrosine kinase inhibitors (TKIs). However, it remains still under investigation which molecular factors may influence CML risk or varying responses to TKIs. The aim of this study was to assess the role of Glutathione-S-transferases (GSTs) genetic polymorphisms in CML susceptibility and TKI...

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Source

Identifiers

PMID: 27454607
DOI: 10.1016/j.canep.2016.07.008

Genes

GSTP1
GSTM1
GSTT1
EFS
ABL1
BCR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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