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Article

Polymorphic variants of GSTM1, GSTT1, and GSTP1 genes in childhood acute leukemias: A preliminary study in Argentina.

Hematology (Amsterdam, Netherlands) - 1 Oct 2015

Weich N, Nuñez M C, Galimberti G, Elena G, Acevedo S, Larripa I, Fundia A F

Abstract excerpt

BACKGROUND AND AIM: Despite recent major advances in leukemia research, the etiopathogenesis of childhood leukemias remains far elusive. Individual predisposing factors, including polymorphisms in detoxification enzymes, have been implicated in the molecular pathogenesis and heterogeneity of the disease. Genetic polymorphisms of glutathione S-transferases (GSTs) that alter enzyme activity could be an additional...

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Source

Identifiers

PMID: 25799091
DOI: 10.1179/1607845415Y.0000000007

Genes

GSTM1
GSTP1
GSTT1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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