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Article

Variations in glutathione-S-transferase genes influence risk of chronic myeloid leukemia.

Hematological oncology - 1 Sept 2012

Özten Nur, Sunguroğlu Asuman, Bosland Maarten C

Abstract excerpt

Glutathione S-transferases (GSTs) are phase II enzymes that detoxify hazardous xenobiotics including carcinogens. Inter-individual variations in GSTM1 and GSTT1 loci have been associated with several types of cancer, including leukemias. In this study, we investigated the possible association between GSTM1 and GSTT1 polymorphisms and susceptibility to chronic myeloid leukemia (CML) in a Turkish population. In a...

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Source

Identifiers

PMID: 21969307
DOI: 10.1002/hon.1018

Genes

GSTM1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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