Article
Impact of GSTT1 and GSTM1 Polymorphisms in the Susceptibility to Philadelphia Negative Chronic Myeloid Leukaemia.
Current cancer drug targets - 1 Jan 2023
Elderdery Abozer Y, Idris Hadeil M E, Tebien Entesar M, Diab Nada Abdalfatah, Hamza Siddiqa M A, Suliman Bandar A, Alhamidi Abdulaziz H, Omer Nawal Eltayeb, Mills Jeremy
Abstract excerpt
BACKGROUND: Our research aimed to clarify the role of genetic polymorphisms in GST (T1 and M1) in the development of Ph-ve CML. MATERIALS AND METHODS: We report on a case-control study with 126 participants, divided into 26 patients with Ph-ve CML (57.7% male, 42.3% female) and 100 healthy volunteers (51% male, 49% female) with no medical history of cancer as a control population. All Ph-ve CML patients were...
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