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Article

Influence of CYP1A1, GST polymorphisms and susceptibility risk of chronic myeloid leukemia in Syrian population.

Medical oncology (Northwood, London, England) - 1 May 2014

Al-Achkar Walid, Azeiz Ghassan, Moassass Faten, Wafa Abdulsamad

Abstract excerpt

In the present study, we investigated the associations of polymorphisms in cytochrome P450 gene (CYP1A1), glutathione S-transferase genes (GSTM1 and GSTT1) with chronic myelogenous leukemia (CML). A total of 126 patients with CML and 172 healthy volunteers were genotyped, and the DNA was isolated from their blood samples. The polymorphisms were assessed by polymerase chain reaction (PCR) restriction fragment...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24671854
DOI: 10.1007/s12032-014-0889-4

Genes

GSTM1
GSTT1

Provenance

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