Article
Therapeutic compounds for Cushing's syndrome: a patent review (2012-2016).
Expert opinion on therapeutic patents - 1 Nov 2016
Ma Li, Yin Lina, Hu Qingzhong
Abstract excerpt
INTRODUCTION: Endogenous Cushing's syndrome (CS) is a set of disorders caused by chronic exposure to excess glucocorticoids induced by neuroendocrine tumors in pituitary, adrenals, and infrequently other sites (ectopic ACTH syndrome). Due to various comorbidities, CS patients exhibit higher risks of cardiovascular diseases and thus increased mortality. Pharmaceutical therapy is an important constituent of...
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