Article

Mitotane Treatment Combined With Unilateral Adrenalectomy in a Patient With Primary Pigmented Nodular Adrenocortical Disease Caused by a Start Codon Mutation of PRKAR1A Gene

2021-10-12

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Primary pigmented nodular adrenocortical disease (PPNAD) is a rare cause of Cushing’s syndrome (CS). This study aimed to explore molecular basis and treatment strategy in a patient with PPNAD.<bold>Methods: </bold>Whole-exome sequencing (WES) was used to reveal the mutation of PRKAR1A gene, with immunohistochemistry (IHC) to observe the expression of mutant PRKA...

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Literature Corpus work: 3a0980ed-bc08-5c2a-b4ff-1b300aabc37b
DOI: 10.21203/rs.3.rs-871643/v1

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Mitotane Treatment Combined With Unilateral Adrenalectomy in a Patient With Primary Pigmented Nodular Adrenocortical Disease Caused by a Start Codon Mutation of PRKAR1A GeneDOI 10.21203/rs.3.rs-871643/v1Read

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