Article

Development of Human Pituitary Adenoma Organoids to Facilitate Effective Targeted Treatments of Cushing's Disease.

2022-06-08

Abstract excerpt

<title>Abstract</title> <p>Cushing's disease (CD) is a serious endocrine disorder caused by dysregulated adrenocorticotropic hormone (ACTH)-secreting pituitary tumor that stimulates the adrenal glands to overproduce cortisol. Chronic exposure to excess cortisol has detrimental effects on health, including increased stroke rates, diabetes, obesity, cognitive impairment, anxiety, depression, and death. The first-li...

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Literature Corpus work: ea5ea87e-20dd-5765-a987-ecf950955429
DOI: 10.21203/rs.3.rs-1663459/v1

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