Article
Risk alleles for IgA nephropathy-associated SNPs conferred completely opposite effects to idiopathic membranous nephropathy in Chinese Han.
Immunologic research - 1 Oct 2017
Qin Xiaosong, Wang Chen, Lu Guanting, Peng Mengle, Cheng Guixue, Zhu Hongquan, Cao Yun, Liu Jianhua, Li Yuzhong, Cai Hong, Yang Funing, Liu Yanhong, Chen Xiaoyu, Li Liubing, Wan Nan, Wen Xiaoting, Li Shijun, Nie Ruili, Qin Dongchun, Li Yongzhe, Liu Yong
Abstract excerpt
The coexistence of immunoglobulin A nephropathy (IgAN) and idiopathic membranous nephropathy (IMN) in a few cases suggested that there could be existed a similar mechanism in pathogenesis of these two types of primary glomerulonephritis. In order to verify this hypothesis, a total of 23 reported IgAN-associated SNPs were genotyped in a cohort of 485 IMN patients and 569 healthy controls with Chinese Han origin....
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