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Characterization of <i>Mycobacterium tuberculosis</i>-specific Th22 cells and the effect of tuberculosis disease and HIV co-infection

2020-10-26

Abstract excerpt

<h4>ABSTRACT</h4> The development of a highly effective tuberculosis (TB) vaccine is likely dependent on our understanding of what constitutes a protective immune response to TB. Accumulating evidence suggests that CD4+ T cells producing IL-22, a distinct subset termed ‘Th22’ cells, may contribute to protective immunity to TB. Thus, we characterized Mycobacterium tuberculosis (Mtb)-specific Th22 (and Th1 and Th17)...

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Literature Corpus work
fbfd32d9-74cc-5106-ab31-64f5676b53ee
DOI
10.1101/2020.10.22.20217521
Open publication

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