Article
A genome-wide association study by ImmunoChip reveals potential modifiers in myelodysplastic syndromes.
Experimental hematology - 1 Nov 2016
Danjou Fabrice, Fozza Claudio, Zoledziewska Magdalena, Mulas Antonella, Corda Giovanna, Contini Salvatore, Dore Fausto, Galleu Antonio, Di Tucci Anna Angela, Caocci Giovanni, Gaviano Eleonora, Latte Giancarlo, Gabbas Attilio, Casula Paolo, Delogu Lucia Gemma, La Nasa Giorgio, Angelucci Emanuele, Cucca Francesco, Longinotti Maurizio
Abstract excerpt
Because different findings suggest that an immune dysregulation plays a role in the pathogenesis of myelodysplastic syndrome (MDS), we analyzed a large cohort of patients from a homogeneous Sardinian population using ImmunoChip, a genotyping array exploring 147,954 single-nucleotide polymorphisms (SNPs) localized in genomic regions displaying some degree of association with immune-mediated diseases or pathways....
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