Back to search

Article

MTHFR act as a potential cancer biomarker in immune checkpoints blockades, heterogeneity, tumor microenvironment and immune infiltration

2023-03-31

Abstract excerpt

<h4>Purpose: </h4> To evaluate the role and landscape of 5-10-Methylenetetrahydrofolate reductase (MTHFR) to immune infiltration, tumor microenvironment, heterogeneity, immune checkpoints blockades, prognostic significance across cancer types. <h4>Methods: </h4> Data sets of genomic, transcriptomic and clinic features of MTHFR across >60,000 patients and up to 44 cancer types were comprehensively analyzed using R...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
4249559b-a662-54ac-bc62-fae0fa441662
DOI
10.21203/rs.3.rs-2744761/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
MTHFR act as a potential cancer biomarker in immune checkpoints blockades, heterogeneity, tumor microenvironment and immune infiltrationDOI 10.21203/rs.3.rs-2744761/v1
The Emerging Role of MTHFD Family Genes in Regulating the Tumor Immunity of Oral Squamous Cell CarcinomaSemantic proximity
Identification of ncRNA-mediated prognostic Value and Immune Infiltration of MTHFD2 in Bladder CancerSemantic proximity
Identification of ncRNA-Mediated Prognostic Value and Functions of MTHFD2 in Bladder CancerSemantic proximity
Identification of MTHFD1L as a potential biomarker for multiple cancers by pan-cancer analysisSemantic proximity
Integrative analysis reveals methylenetetrahydrofolate dehydrogenase 1-like as an independent shared diagnostic and prognostic biomarker in five different human cancersSemantic proximity
Functional germline variants in DNA damage repair pathways are associated with altered survival in adults with glioma treated with temozolomideSemantic proximity
Pan-Cancer Analysis of Molecular Characteristics and Oncogenic Role of PRMT5 in Human CancersSemantic proximity
Identification of MTHFD2 as a Prognostic Factor and Evaluation of its Role in Macrophage Polarization in Kidney Renal Clear Cell Carcinoma by Pan-Cancer AnalysisSemantic proximity
Age, sex, and specific gene mutations affect the effects of immune checkpoint inhibitors in colorectal cancer.Semantic proximity
Mutational burden, immune checkpoint expression, and mismatch repair in glioma: implications for immune checkpoint immunotherapy.Semantic proximity
Up-regulated Expression of MTHFD2 Correlates with Favorable Prognosis in LGG Patients: A Bioinformatic AnalysisSemantic proximity
Functional germline variants in DNA damage repair pathways are associated with altered survival in adults with glioma treated with temozolomide.Semantic proximity
Select a neighboring publication to make it the new centre.