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Article

Identification of methylguanine methyltransferase polymorphisms as genetic markers of individual susceptibility to therapy-related myeloid neoplasms.

European journal of cancer (Oxford, England : 1990) - 1 Jan 2014

Dubois Julie, Etienne Gabriel, Laroche-Clary Audrey, Lascaux Axelle, Bidet Audrey, Lippert Eric, Ait-ouferoukh Sofiane, Saada Veronique, Micol Jean-Baptiste, Bouabdallah Krimo, Robert Jacques

Abstract excerpt

PURPOSE: Myelodysplastic syndromes (MDS) are pre-leukaemic haematopoietic stem cell disorders. Among them, 10-20% occur after chemotherapy and/or radiotherapy, and are called 'therapy-related MDS' (t-MDS). The aim of this study was to identify genetic markers in t-MDS. METHODS: A prospective cohort of 59 MDS patients (39 de novo MDS, 20 t-MDS) was studied. A total of 384 single nucleotide polymorphisms (SNP)...

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PMID: 24238921
DOI: 10.1016/j.ejca.2013.10.012

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MGMT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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