Article
Dynamin controls extracellular level of Awd/Nme1 metastasis suppressor protein.
Naunyn-Schmiedeberg's archives of pharmacology - 1 Nov 2016
Romani Patrizia, Papi Alessio, Ignesti Marilena, Soccolini Giulia, Hsu Tien, Gargiulo Giuseppe, Spisni Enzo, Cavaliere Valeria
Abstract excerpt
Dynamin GTPase (Dyn) plays a critical role in membrane-remodelling events underlying endocytosis. Studies in Drosophila identified a functional interaction between the Dyn homologue, encoded by the shibire (shi) gene, and Abnormal wing discs (Awd), a nucleoside diphosphate kinase (NDPK) that is the homologue of group I Nme human genes. These Drosophila studies showed that awd mutations enhance mutant shi...
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