Article
The rs12917707 polymorphism at the UMOD locus and glomerular filtration rate in individuals with type 2 diabetes: evidence of heterogeneity across two different European populations.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Oct 2017
Prudente Sabrina, Di Paola Rosa, Copetti Massimiliano, Lucchesi Daniela, Lamacchia Olga, Pezzilli Serena, Mercuri Luana, Alberico Federica, Giusti Laura, Garofolo Monia, Penno Giuseppe, Cignarelli Mauro, De Cosmo Salvatore, Trischitta Vincenzo
Abstract excerpt
BACKGROUND: UMOD variability has been associated at a genome-wide level of statistical significance with glomerular filtration rate (GFR) in Swedish individuals with type 2 diabetes (T2D; n = 4888). Whether this finding is extensible also to diabetic patients from other populations deserves further study. Our aim was to investigate the relationship between UMOD variability and GFR in patients with T2D from Italy....
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