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Article

Next generation sequencing search for uromodulin gene variants related with impaired renal function.

Molecular biology reports - 1 Sept 2015

Gómez Juan, Díaz-Corte Carmen, Tranche Salvador, Alvarez Francisco, Iglesias Sara, Alonso Belén, Coto Eliecer

Abstract excerpt

Uromodulin gene (UMOD) mutations have been linked to rare forms of mendelian dominant medullary cystic kidney disease and familial hyperuricemia. In addition, common single nucleotide polymorphisms in the UMOD promoter have been associated with the risk for impaired renal function and chronic kidney disease. Our main purpose was to identify UMOD variants related with impaired renal function in an elderly...

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Source

Identifiers

PMID: 26040415
DOI: 10.1007/s11033-015-3883-9

Genes

UMOD

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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