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Article

NALP3-Inflammasome-Related Gene Polymorphisms in Patients with Prehypertension and Coronary Atherosclerosis.

BioMed research international - 1 Jan 2016

Zhao Xin, Gu Chonghuai, Yan Chenghui, Zhang Xiaolin, Li Yi, Wang Li, Ren Lili, Zhang Yan, Peng Junyin, Zhu Zhiming, Han Yaling

Abstract excerpt

Objectives. Prehypertension is an early stage of hypertension that is characterized by inflammatory factors. Inflammation also plays an essential role in the development of coronary atherosclerosis (CAS). The present study evaluated the NALP3-inflammasome and its related genes, NLRP3, NOD2, and CARD8, using SNP linkage and gene haplotypes in prehypertensive patients. Methods. A total of 576 patients with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27446957
DOI: 10.1155/2016/7395627
PMCID: PMC4944040

Genes

NOD2
CARD8
NLRP3
CRP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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