Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

NLRP3 Inflammasome Polymorphism and Macrovascular Complications in Type 2 Diabetes Patients.

Journal of diabetes research - 1 Jan 2015

Klen Jasna, Goričar Katja, Janež Andrej, Dolžan Vita

Abstract excerpt

BACKGROUND: It is generally accepted that poor glycemic control, arterial hypertension and/or hyperlipidemia, and the associated oxidative stress may contribute to the development of macro- and microvascular complications in type 2 diabetes (T2D). Such metabolic damage signals may activate inflammasome and trigger chronic inflammation. We investigated common polymorphisms in inflammasome coding genes and the risk...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blood Glucose
Share to Diabetes Complications
Share to Inflammasomes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lipids

Share to Myocardial Infarction

Share to NLR Family, Pyrin Domain-Containing 3 Protein

Share to Regression Analysis

Share to Vascular Diseases

Source

Open in PubMed Open full text

Identifiers

PMID: 26273672
DOI: 10.1155/2015/616747
PMCID: PMC4530261

Genes

NLRP3
CARD8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

NLRP3 Inflammasome Polymorphism and Macrovascular Complications in Type 2 Diabetes Patients.PMID 26273672Read ↗

NLRP3-Inflammasome Gene Variations in the Risk of Type 2 Diabetes.Semantic proximity Read ↗

Emerging Role of LncRNA Regulation for NLRP3 Inflammasome in Diabetes ComplicationsSemantic proximity Read ↗

Role of the NLRP3 inflammasome in diabetes and its complications (Review)Semantic proximity Read ↗

Genetic variation in CARD8, a gene coding for an NLRP3 inflammasome-associated protein, alters the genetic risk for diabetic nephropathy in the context of type 2 diabetes mellitus.Semantic proximity Read ↗

Role of variants rs5030717 and rs5030718 of TLR4 in the risk prediction of nephropathy, hypertension and dyslipidaemia in type 2 diabetes mellitus.Semantic proximity Read ↗

Proteasome modulator 9 and macrovascular pathology of T2D.Semantic proximity Read ↗

Genetically determined NLRP3 inflammasome activation associates with systemic inflammation and cardiovascular mortalitySemantic proximity Read ↗

NALP3-Inflammasome-Related Gene Polymorphisms in Patients with Prehypertension and Coronary Atherosclerosis.Semantic proximity Read ↗

Mediterranean Diet, Glucose Homeostasis, and Inflammasome Genetic Variants: The CORDIOPREV Study.Semantic proximity Read ↗

The NLRP3 inflammasome rs35829419 C>A polymorphism is associated with type 2 diabetes mellitus in Saudi Arabia.Semantic proximity Read ↗

Multifactorial Activation of NLRP3 Inflammasome: Relevance for a Precision Approach to Atherosclerotic Cardiovascular Risk and DiseaseSemantic proximity Read ↗

TLR4 polymorphisms seem not to be associated with prediabetes and type 2 diabetes but predispose to diabetic retinopathy; TLR4 polymorphisms in glucose continuum.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.