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Incorporating Advances in Molecular Pathology Into Brain Tumor Diagnostics

9 Mar 2018

Abstract excerpt

Recent advances in molecular pathology have reshaped the practice of brain tumor diagnostics. The classification of gliomas has been restructured with the discovery of isocitrate dehydrogenase (IDH) 1/2 mutations in the vast majority of lower grade infiltrating gliomas and secondary glioblastomas (GBM), with IDH-mutant astrocytomas further characterized by TP53 and ATRX mutations. Whole-arm 1p/19q codeletion in...

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PMID: 29521646
DOI: 10.1097/pap.0000000000000186

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