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Article

WASH has a critical role in NK cell cytotoxicity through Lck-mediated phosphorylation.

Cell death & disease - 21 Jul 2016

Huang L, Zhu P, Xia P, Fan Z

Abstract excerpt

Natural killer (NK) cells are important effector cells of the innate immune system to kill certain virus-infected and transformed cells. Wiskott-Aldrich Syndrome protein (WASP) and SCAR homolog (WASH) has been identified as a member of WASP family proteins implicated in regulating the cytoskeletal reorganization, yet little is known about its function in lymphocytes. Here we demonstrate that WASH is crucial for...

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Identifiers

PMID: 27441653
DOI: 10.1038/cddis.2016.212
PMCID: PMC4973352

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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WASH has a critical role in NK cell cytotoxicity through Lck-mediated phosphorylation.PMID 27441653Read ↗

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