Article
Maturation of suprathreshold auditory nerve activity involves cochlear CGRP-receptor complex formation.
Physiological reports - 1 Jul 2016
Dickerson Ian M, Bussey-Gaborski Rhiannon, Holt Joseph C, Jordan Paivi M, Luebke Anne E
Abstract excerpt
In adult animals, the neuropeptide calcitonin gene-related peptide (CGRP) is contained in cochlear efferent fibers projecting out to the cochlea, and contributes to increased suprathreshold sound-evoked activity in the adult auditory nerve. Similarly, CGRP applied to the lateral-line organ (hair cell organ) increases afferent nerve activity in adult frogs (post-metamorphic day 30), yet this increase is...
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