Article
Progressive hearing loss in mice carrying a mutation in the p75 gene.
Brain research - 26 May 2006
Sato Takashi, Doi Katsumi, Taniguchi Manabu, Yamashita Toshihide, Kubo Takeshi, Tohyama Masaya
Abstract excerpt
The neurotrophin receptor p75 (p75NTR) is expressed in the developmental stage of the cochlea. However, the role of the p75NTR in the inner ear remains to be established. In this study, we conducted electrophysiological and morphological analyses of the auditory function of mice carrying a mutation in the p75 gene at different longitudinal stages. The mice carrying a mutation in the p75 gene showed an age-related...
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