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Article

Changes in White Matter Organization in Adolescent Offspring of Schizophrenia Patients.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Jan 2017

de Leeuw Max, Bohlken Marc M, Mandl René Cw, Hillegers Manon Hj, Kahn René S, Vink Matthijs

Abstract excerpt

Schizophrenia is associated with frontostriatal network impairments underlying clinical and cognitive symptoms. We previously found disruptions in anatomical pathways, including the tract connecting the left nucleus accumbens and left dorsolateral prefrontal cortex (DLPFC). Similar deficits are observed in unaffected siblings of schizophrenia patients, indicating that these deficits are linked to a genetic...

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Identifiers

PMID: 27440007
DOI: 10.1038/npp.2016.130
PMCID: PMC5399227

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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