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Article

Developmental disruptions in neural connectivity in the pathophysiology of schizophrenia.

Development and psychopathology - 1 Jan 2008

Karlsgodt Katherine H, Sun Daqiang, Jimenez Amy M, Lutkenhoff Evan S, Willhite Rachael, van Erp Theo G M, Cannon Tyrone D

Abstract excerpt

Schizophrenia has been thought of as a disorder of reduced functional and structural connectivity. Recent advances in neuroimaging techniques such as functional magnetic resonance imaging, structural magnetic resonance imaging, diffusion tensor imaging, and small animal imaging have advanced our ability to investigate this hypothesis. Moreover, the power of longitudinal designs possible with these noninvasive...

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PMID: 18838043
DOI: 10.1017/S095457940800062X

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