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Decreased left middle temporal gyrus volume in antipsychotic drug-naive, first-episode schizophrenia patients and their healthy unaffected siblings.

Schizophrenia research - 1 Mar 2013

Hu Maorong, Li Jun, Eyler Lisa, Guo Xiaofeng, Wei Qingling, Tang Jingsong, Liu Feng, He Zhong, Li Lihua, Jin Hua, Liu Zhening, Wang Juan, Liu Fang, Chen Huafu, Zhao Jingping

Abstract excerpt

BACKGROUND: The shared neuropathological characteristics of patients with schizophrenia and their siblings might represent intermediate phenotypes that could be used to investigate genetic susceptibility to the illness. We sought to discover gray matter volume differences in patients with schizophrenia and their unaffected siblings with voxel-based morphometry (VBM). METHODS: We recruited antipsychotic...

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Identifiers

PMID: 23360727
DOI: 10.1016/j.schres.2012.12.018

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FES

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