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A family affair: brain abnormalities in siblings of patients with schizophrenia

22 May 2013

Abstract excerpt

Schizophrenia is a severe mental disorder that has a strong genetic basis. Converging evidence suggests that schizophrenia is a progressive neurodevelopmental disorder, with earlier onset cases resulting in more profound brain abnormalities. Siblings of patients with schizophrenia provide an invaluable resource for differentiating between trait and state markers, thus highlighting possible endophenotypes for...

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PMID: 23698280
DOI: 10.1093/brain/awt116

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