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Article

Alterations in the cerebral white matter of genetic high risk offspring of patients with schizophrenia spectrum disorder.

Progress in neuro-psychopharmacology & biological psychiatry - 10 Jan 2013

Francis Alan N, Bhojraj Tejas S, Prasad Konasale M, Montrose Debra, Eack Shaun M, Rajarethinam Rajaprabhakaran, van Elst Ludger T, Keshavan Matcheri S

Abstract excerpt

Alterations in white matter (WM) may be seen in young relatives at risk and may underlie vulnerability to schizophrenia. We were interested in exploring which of the WM regions were altered in adolescent offspring at familial risk for schizophrenia. We examined structural alterations in the offspring of subjects with schizophrenia or schizoaffective disorder (HR; n=65; 36 males) and healthy controls (HC; n=80: 37...

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Identifiers

PMID: 22910323
DOI: 10.1016/j.pnpbp.2012.08.003
PMCID: PMC3635091

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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