Article
Set7 mediated interactions regulate transcriptional networks in embryonic stem cells.
Nucleic acids research - 2 Nov 2016
Tuano Natasha K, Okabe Jun, Ziemann Mark, Cooper Mark E, El-Osta Assam
Abstract excerpt
Histone methylation by lysine methyltransferase enzymes regulate the expression of genes implicated in lineage specificity and cellular differentiation. While it is known that Set7 catalyzes mono-methylation of histone and non-histone proteins, the functional importance of this enzyme in stem cell differentiation remains poorly understood. We show Set7 expression is increased during mouse embryonic stem cell...
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