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Article

The histone methyltransferase Set7/9 promotes myoblast differentiation and myofibril assembly.

The Journal of cell biology - 22 Aug 2011

Tao Yazhong, Neppl Ronald L, Huang Zhan-Peng, Chen Jianfu, Tang Ru-Hang, Cao Ru, Zhang Yi, Jin Suk-Won, Wang Da-Zhi

Abstract excerpt

The molecular events that modulate chromatin structure during skeletal muscle differentiation are still poorly understood. We report in this paper that expression of the H3-K4 histone methyltransferase Set7 is increased when myoblasts differentiate into myotubes and is required for skeletal muscle development, expression of muscle contractile proteins, and myofibril assembly. Knockdown of Set7 or expression of a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21859860
DOI: 10.1083/jcb.201010090
PMCID: PMC3160588

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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