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Defining the identity of mouse embryonic dermal fibroblasts

6 Jun 2016

Abstract excerpt

Embryonic dermal fibroblasts in the skin have the exceptional ability to initiate hair follicle morphogenesis and contribute to scarless wound healing. Activation of the Wnt signaling pathway is critical for dermal fibroblast fate selection and hair follicle induction. In humans, mutations in Wnt pathway components and target genes lead to congenital focal dermal hypoplasias with diminished hair. The gene...

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PMID: 27265328
DOI: 10.1002/dvg.22952

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