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Article

SNP of HMGCR and Apo E genes and their impact in response to statin therapy in hypercholesterolemic and hypertriglyceridemic patients in Pakistan.

Pakistan journal of pharmaceutical sciences - 1 Jul 2021

Rizwan Muhammad, Aslam Nosheen, Ashfaq Usman Ali, Hayat Muhammad, Hussain Syed Makhdoom

Abstract excerpt

Coronary artery disease (CAD) and the problems associated with it are the most prominent causes of death in the whole world. Statins are accustomed to lower lipid levels in CAD patients. The target of this study was to analyze whether or not common variations in HMGCoA Reductase (HMGCR) and Apolipoprotein E (ApoE) genes are responsible for metabolism of lipid and statin that modify the impact of statins on serum...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34799335

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