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Article

High Sensitivity Crosslink Detection Coupled With Integrative Structure Modeling in the Mass Spec Studio.

Molecular & cellular proteomics : MCP - 1 Sept 2016

Sarpe Vladimir, Rafiei Atefeh, Hepburn Morgan, Ostan Nicholas, Schryvers Anthony B, Schriemer David C

Abstract excerpt

The Mass Spec Studio package was designed to support the extraction of hydrogen-deuterium exchange and covalent labeling data for a range of mass spectrometry (MS)-based workflows, to integrate with restraint-driven protein modeling activities. In this report, we present an extension of the underlying Studio framework and provide a plug-in for crosslink (XL) detection. To accommodate flexibility in XL methods and...

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Identifiers

PMID: 27412762
DOI: 10.1074/mcp.O116.058685
PMCID: PMC5013318

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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