Article

XL-MS–Guided Structure Prediction of Disordered <i>Encephalitozoon hellem</i> Proteins

2026-06-12

Abstract excerpt

Microsporidia such as Encephalitozoon hellem are obligate intracellular human parasites that remain genetically intractable, limiting functional characterization of their proteomes. Structural studies based on homology-based modeling and the use of deep learning algorithms of microsporidian proteins also remain limited because most have little to no sequence similarity to proteins with solved structures. To addr...

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Literature Corpus work: 09b7a483-acff-5a53-a5fb-6ce9d5e51ed4
DOI: 10.64898/2026.06.11.731626

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