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Article

Stroke sensitivity in the aged: sex chromosome complement vs. gonadal hormones.

Aging - 1 Jul 2016

McCullough Louise D, Mirza Mehwish A, Xu Yan, Bentivegna Kathryn, Steffens Eleanor B, Ritzel Rodney, Liu Fudong

Abstract excerpt

Stroke is a sexually dimorphic disease. Elderly women not only have higher stroke incidence than age-matched men, but also have poorer recovery and higher morbidity and mortality after stroke. In older, post-menopausal women, gonadal hormone levels are similar to that of men. This suggests that tissue damage and functional outcomes are influenced by biologic sex (XX vs. XY) rather than the hormonal milieu at...

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Identifiers

PMID: 27405096
DOI: 10.18632/aging.100997
PMCID: PMC4993340

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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