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Article

The heterozygous A53T mutation in the alpha-synuclein gene in a Chinese Han patient with Parkinson disease: case report and literature review.

Journal of neurology - 1 Oct 2016

Xiong Wei-Xi, Sun Yi-Min, Guan Rong-Yuan, Luo Su-Shan, Chen Chen, An Yu, Wang Jian, Wu Jian-Jun

Abstract excerpt

The missense mutation A53T of alpha-synuclein gene (SNCA) was reported to be a rare but definite cause of sporadic and familial Parkinson disease (PD). It seemed to be restricted geographically in Greece and Italy. We aimed to identify the SNCA mutations in a Chinese PD cohort. Ninety-one early onset PD patients or familial PD probands were collected consecutively for the screening of PD-related genes. The...

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Source

Identifiers

PMID: 27393118
DOI: 10.1007/s00415-016-8213-1

Genes

SNCA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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