Article
Link between the SNCA gene and parkinsonism.
Neurobiology of aging - 1 Mar 2015
Xu Wei, Tan Lan, Yu Jin-Tai
Abstract excerpt
The groundbreaking discovery of mutations in the SNCA gene in a rare familial form of Parkinson's disease (PD) has revolutionized our basic understanding of the etiology of PD and other related disorders. Genome-wide Association Studies has demonstrated a wide array of single-nucleotide polymorphisms associated with the increasing risk of developing the more common type, sporadic PD, further corroborating the...
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