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Genetic analysis of SNCA coding mutation in Chinese Han patients with Parkinson disease.

Acta neurologica Belgica - 1 Sept 2015

Deng Sheng, Deng Xiong, Yuan Lamei, Song Zhi, Yang Zhijian, Xiong Wei, Deng Hao

Abstract excerpt

Parkinson disease (PD) is the second most common progressive neurodegenerative disorder. It is characterized by selective loss of dopamine-producing neurons and aggregation of alpha-synuclein (SNCA) in neurons of particular brain regions. At least 20 loci and 15 disease-causing genes have been identified. Rare missense or multiplication mutations in the SNCA gene have been reported to be involved in some familial...

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Identifiers

PMID: 25092551
DOI: 10.1007/s13760-014-0347-2

Genes

SNCA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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