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Article

Carboxyl-terminal truncated HBx contributes to invasion and metastasis via deregulating metastasis suppressors in hepatocellular carcinoma.

Oncotarget - 23 Aug 2016

Li Weihua, Li Man, Liao Dongjiang, Lu Xinpeng, Gu Xia, Zhang Qianqian, Zhang Zhixiang, Li Hui

Abstract excerpt

Hepatitis B virus (HBV) X protein (HBx), a trans-regulator, is frequently expressed in truncated form without carboxyl-terminus in hepatocellular carcinoma (HCC), but its functional mechanisms are not fully defined. In this report, we investigated frequency of this natural HBx mutant in HCCs and its functional significance. In 102 HBV-infected patients with HCC, C-terminal truncation of HBx, in contrast to...

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Identifiers

PMID: 27391153
DOI: 10.18632/oncotarget.10399
PMCID: PMC5342405

Genes

MAZ
CAPZB

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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