Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Systematic protein-protein interaction and pathway analyses in the idiopathic inflammatory myopathies.

Arthritis research & therapy - 7 Jul 2016

Parkes Joanna E, Rothwell Simon, Day Philip J, McHugh Neil J, Betteridge Zoë E, Cooper Robert G, Ollier William E, Chinoy Hector, Lamb Janine A

Abstract excerpt

BACKGROUND: The idiopathic inflammatory myopathies (IIM) are autoimmune diseases characterised by acquired proximal muscle weakness, inflammatory cell infiltrates in muscle and myositis-specific/associated autoantibodies. It is unclear which pathways are involved in IIM, and the functional relationship between autoantibody targets has not been systematically explored. Protein-protein interaction and pathway...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autoantibodies
Share to Autoantigens

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to TRAF6 gene

Share to Myositis

Share to Polymorphism, Single Nucleotide

Share to Protein Interaction Mapping

Share to Protein Interaction Maps

Source

Open in PubMed Open full text

Identifiers

PMID: 27388770
DOI: 10.1186/s13075-016-1061-7
PMCID: PMC4936183

Genes

PSMD3
TRAF6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Systematic protein-protein interaction and pathway analyses in the idiopathic inflammatory myopathies.PMID 27388770Read ↗

Genetic Architecture of Idiopathic Inflammatory Myopathies From Meta-Analyses.Semantic proximity Read ↗

Plasma proteome reflects tissue damage and clinical manifestations in patients with inflammatory myopathiesSemantic proximity Read ↗

Dense genotyping of immune-related loci in idiopathic inflammatory myopathies confirms HLA alleles as the strongest genetic risk factor and suggests different genetic background for major clinical subgroups.Semantic proximity Read ↗

The Genetics of Autoimmune MyositisSemantic proximity Read ↗

Molecular profiles of inflammatory myopathiesSemantic proximity Read ↗

Pleiotropy and Disease Interactors: The Dual Nature of Genes Linking Ageing and Ageing-related DiseasesSemantic proximity Read ↗

Identification of genetic variants associated with idiopathic inflammatory myopathies via cross-trait analysis with B cell lymphomasSemantic proximity Read ↗

Unveiling the Molecular Landscape: Network Analysis of Genes, Proteins, and Transcription Factors in Primary Progressive and Secondary Progressive Multiple Sclerosis for Unraveling Disease Progression and Prognostic FactorsSemantic proximity Read ↗

Genetic analyses of inflammatory polyneuropathy and chronic inflammatory demyelinating polyradiculoneuropathy identified candidate genesSemantic proximity Read ↗

Identification of Novel Associations and Localization of Signals in Idiopathic Inflammatory Myopathies Using Genome-Wide Imputation.Semantic proximity Read ↗

Shared genetic susceptibility between idiopathic inflammatory myopathies and common B cell lymphoma subtypes found primarily in the human leucocyte antigen region.Semantic proximity Read ↗

Protein-protein interaction analysis highlights additional loci of interest for multiple sclerosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.