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Article

Protein-protein interaction analysis highlights additional loci of interest for multiple sclerosis.

PloS one - 1 Jan 2012

Ragnedda Giammario, Disanto Giulio, Giovannoni Gavin, Ebers George C, Sotgiu Stefano, Ramagopalan Sreeram V

Abstract excerpt

Genetic factors play an important role in determining the risk of multiple sclerosis (MS). The strongest genetic association in MS is located within the major histocompatibility complex class II region (MHC), but more than 50 MS loci of modest effect located outside the MHC have now been identified. However, the relative candidate genes that underlie these associations and their functions are largely unknown. We...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23094030
DOI: 10.1371/journal.pone.0046730
PMCID: PMC3475710

Genes

CHST12
SYK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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