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Article

Molecular profiles of inflammatory myopathies

22 Oct 2002

Abstract excerpt

OBJECTIVE: To describe the use of large-scale gene expression profiles to distinguish broad categories of myopathy and subtypes of inflammatory myopathies (IM) and to provide insight into the pathogenesis of inclusion body myositis (IBM), polymyositis, and dermatomyositis. METHODS: Using Affymetrix GeneChip microarrays, the authors measured the simultaneous expression of approximately 10,000 genes in muscle...

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PMID: 12391344
DOI: 10.1212/wnl.59.8.1170

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