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Article

Whole genome sequencing of hepatitis C virus from dried blood spots by hybrid capture for genotype and antiviral resistance determination.

Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology - 1 Aug 2026

Phillips Catherine, Brown Benjamin, Machin Nicholas, Bibby David F, Mbisa Jean L, Davies Emma Ann

Abstract excerpt

BACKGROUND: Dried blood spot (DBS) testing enables hepatitis C virus (HCV) testing in hard‑to‑reach patient populations but typically lacks full genotype and drug resistance information. This study evaluates a commercially available hybrid‑capture whole‑genome sequencing (WGS) workflow for HCV from DBS to determine suitability for clinical diagnostic and surveillance purposes. METHODS: We analysed 147 DBS and 24...

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Share to Antiviral Agents
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 42419095
DOI: 10.1016/j.jcv.2026.105972

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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