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Article

miR-151-5p, targeting chromatin remodeler SMARCA5, as a marker for the BRCAness phenotype.

Oncotarget - 6 Dec 2016

Tommasi Stefania, Pinto Rosamaria, Danza Katia, Pilato Brunella, Palumbo Orazio, Micale Lucia, De Summa Simona

Abstract excerpt

In recent years, the assessment of biomarkers useful for "precision medicine" has been a hot topic in research. The involvement of microRNAs in the pathogenesis of breast cancer has been highly investigated with the aim of being able to molecularly stratify this highly heterogeneous disease. Our aim was to identify microRNAs targeting DNA repair machinery, through Affymetrix GeneChip miRNA Arrays, in a cohort of...

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Topics

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Share to Adenosine Triphosphatases
Share to BRCA1 Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to BRCA2 Protein

Share to Chromatin Assembly and Disassembly

Share to Chromosomal Proteins, Non-Histone

Share to MCF-7 Cells

Share to MicroRNAs

Share to Poly (ADP-Ribose) Polymerase-1

Source

Open in PubMed Open full text

Identifiers

PMID: 27385001
DOI: 10.18632/oncotarget.10345
PMCID: PMC5348325

Genes

PARP1
SMARCA5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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